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Milestones: E-news from the University of Wisconsin Department of Pediatrics
JUNE 2018

Contents


Top Stories: Pediatrics Research Day Highlights  |  Outstanding Showing at PAS Meeting  |  Iams Lectureship Speaker Eric Post, PhD, ATC, Focuses on Youth Sports Specialization

In the News: Dr. Christian Capitini Featured on CAR T-cell Therapy for Resistant ALL  |  Dr. Dipesh Navsaria Comments on SNAP Requirements, Policy Proposals  |  Casey Reiser Celebrates Master of Genetic Counselor Studies Program's 40th Anniversary  |  Dr. Ellen Wald on Appropriate Use for ENT Infections

Honors and Awards: Two Students in Dr. Marlowe Eldridge's Lab Receive Awards at APS Experimental Biology Meeting   |  Dr. Gregory Rice Elected a Graduation "Hooder" at SMPH Recognition Ceremony

Wellness Tip: Aligning Personal and Professional Values with Work Roles

Learner Tribute: Bikash Pattnaik, PhD

Hi-5 from a Colleague: Megan Peters, MD

New Grants

New Publications

New Faculty and Staff: Katherine Lemon, MD; Queenie Tan, MD; Jamee Schoephoerster

Top Stories

Spring Research Day

A resonant keynote address from Megan Moreno, MD, MSEd, MPH, and a 27 percent increase in abstracts from faculty and learners were among the highlights of the Department of Pediatrics’ 2018 Spring Research Day, held Friday, June 1, 2018, at the Health Sciences Learning Center (HSLC).

In her presentation, “Bloom," Dr. Moreno---the department's vice chair of digital health and the academic division chief for General Pediatrics and Adolescent Medicine---acknowledged the many paths to research that learners and practicing clinicians might take in their career. 

To encourage more clinicians to engage in research, she shared three observations: that studies suggest academic physicians have lower rates of burnout and stagnation; that research ideas flow from clinical experience and back to the clinic; and that research provides a path to improve care for patients a clinician will never meet. She then offered 10 reasons why clinic skills are great preparation for research. 

“Each of you has a story or experience you can return to center your own strength, and I encourage you to hold on to and return to that,” she concluded. “Whatever pace is yours, whatever path is yours – you got this."

The day continued with six oral presentations by faculty and learners. In total, it included 90 abstracts by faculty, fellows and residents, a 27 percent increase from 2017. Of these, 55 (61%) were accepted at the Pediatric Academic Societies (PAS) meeting: 44 as poster presentations, 10 as platform presentations and one as a workshop.

Sixty-three of those abstracts were displayed as research posters in the HSLC atrium throughout Friday afternoon.

Full story and slideshow…

Department Has Outstanding Showing at Pediatric Academic Societies Meeting

The Department of Pediatrics’ research and academic achievements were on full display at the Pediatric Academic Societies (PAS) meeting, held May 5-8, 2018, in Toronto, Canada.

David Allen, MDDivision of Endocrinology and Diabetes Chief David Allen, MD, was this year’s recipient of the American Academy of Pediatrics (AAP) and Pediatric Endocrine Society (PES) Paul Kaplowitz Endowed Lectureship for Quality Care. He presented a plenary session, “Growth-Promoting Treatment: When Discretion is the Better Part of Value.”

The outstanding showing by department faculty, residents and staff also included 11 platform presentations, three invited science sessions, two special-interest groups, two workshops and 54 posters.

Above: Dr. Mary Ehlenbach at the PAS meeting with her poster on predictors of emergency department diversions for children with medical complexity in a complex care program.
 

Iams Lectureship Speaker Eric Post, PhD, ATC, Focuses on Youth Sports Specialization

The University of Wisconsin Department of Pediatrics welcomed Eric Post, PhD, ATC, as its Grand Rounds speaker for the 2018 Alexander M. Iams Lectureship in Pediatric Practice, held May 10, 2018.

Dr. Post is an athletic trainer at the University Health Services Athletic Training Clinic, a research assistant in the UW-Madison Wisconsin Injury in Sport Laboratory and a lecturer in the Department of Kinesiology.

His presentation, “The Who, What, and Why of Sport Specialization,” educated attendees on the prevalence, factors and injuries associated with youth sport specialization, defined as “year-round intensive training in a single sport at the exclusion of other sports.”

Dr. Post shared American Academy of Pediatrics recommendations that parents delay their children’s sport specialization until age 15-16, to monitor that elite sports programs aren’t over-stressing their child and to encourage their children to take time off from their sport each week and for three months per year.

Above: Jay Iams, MD (the son of Alexander M. Iams, MD), and Eric Post, PhD, ATC.
 

In the News

 

Christian Capitini, MDDr. Christian Capitini Featured in Wisconsin State Journal Article on CAR T-cell Therapy for Resistant ALL

Christian Capitini, MD (Assistant Professor, Division of Hematology, Oncology & Bone Marrow Transplant), was among UW Health physicians and staff featured in a Wisconsin State Journal article on CAR T-cell therapy, a promising new immunotherapy for resistant acute lymphoblastic leukemia (ALL). The article profiled two young patients who were the first to receive CAR T-cell therapy in Wisconsin since it was approved last year. UW Health is the only place providing it in the state. The treatment, called Kymriah, is “a paradigm-shifting game changer,” Dr. Capitini said. Full story…
 

Dipesh Navsaria, MPH, MSLIS, MDDr. Dipesh Navsaria Comments on SNAP Requirements, Policy Proposals in Cap Times Columns

In a recent Cap Times column, Dipesh Navsaria, MPH, MSLIS, MD (Associate Professor [CHS], Division of General Pediatrics & Adolescent Medicine), commented on the Legislative Fiscal Bureau’s analysis of proposed work and job training requirements in the 2018 federal “farm bill” for families to continue receiving Supplemental Nutrition Assistance Program (SNAP) benefits. These requirements "would likely deprive 11.1 percent of recipients of food through lost eligibility, almost 76,000 individuals in Wisconsin alone," he wrote. Full story...

In another column, Dr. Navsaria commented on two proposed federal policy initiatives: one to separate parents and children who present to U.S. borders, and one to consider use of publicly funded services such as Medicaid or SNAP against those who apply for visa, permanent resident status, or citizenship. Full story...
 

Casey Reiser, MS, CGCCasey Reiser Celebrates the Master of Genetic Counselor Studies Program in SMPH Quarterly

In the most recent issue of Quarterly, the UW School of Medicine and Public Health (SMPH) alumni magazine, Catherine "Casey" Reiser, MS, CGC (Associate Professor [CHS], Division of Genetics and Metabolism), celebrates the Master of Genetic Counselor Studies program, which graduated its 40th class in May. "It’s a major milestone by any standards, even if you consider that UW-Madison’s program was the first in the Midwest and the eighth in the United States (only five of which remain open)," said Reiser, an alumna of the program and now its director. Full story...
 

Ellen Wald, MDDr. Ellen Wald Comments on Appropriate Antibiotic Use for ENT Infections in Infectious Diseases in Children 

In the April 2018 issue of Infectious Diseases in Children, Department of Pediatrics Chair Ellen Wald, MD, commented on diagnostic criteria, appropriate antibiotic prescribing practices and when to consult a specialist for children who have ear, nose and throat infections. Noting that uncomplicated colds, complicated colds and acute otitis media are all often accompanied by similar symptoms, she said, "as a pediatrician, you have to do the best that you can to explain to the parent what you are seeing and why you do not think antibiotics are indicated in any given situation." Full story...

Honors and Awards

 

Two Students in Dr. Marlowe Eldridge's Lab Receive Awards at APS Experimental Biology Meeting

UW-Madison undergraduate students Karly Katchen, Alexandra Carl, Caitlin Jarrard and Rachel Harradine pose for a photo in at the Experimental Biology meeting in San Diego. Harradine and Jarrard are students in the lab of Marlowe Eldridge, MD.Two UW-Madison undergraduate students in the lab of Marlowe Eldridge, MD (Professor, Division of Pediatric Critical Care Medicine), were recognized during the American Physiological Society’s Experimental Biology meeting in San Diego.

Caitlin Jarrard (pictured, third from left) and Rachel Harradine (pictured, at far right) were 2018 Barbara A. Horwitz and John M. Horowitz Outstanding Undergraduate Abstract Awardees. Jarrard also was awarded the Excellence in Undergraduate Research Awards based on her oral presentation. Full story...
 

Greg Rice, MDDr. Gregory Rice Elected a Graduation "Hooder" at SMPH Recognition Ceremony

Gregory Rice, MD (Associate Professor [CHS], Division of Genetics and Metabolism), was a graduation “hooder” at the UW School of Medicine and Public Health (SMPH) recognition ceremony on May 11, 2018. Dr. Rice was elected by the fourth-year students to represent SMPH basic science faculty at the ceremony.

Wellness Tip 


Sarah Webber, MD

Aligning Personal and Professional Values with Work Roles

Meaning in work is defined as “the value of a work goal or purpose, judged in relation to an individual’s own ideals or standards” (Thomas & Velthouse 1990). Connecting to meaning in one’s work is one of many strategies to improve professional fulfillment and well-being. After years of training and practice, connecting to what was once meaningful about one’s work can be challenging. A lack of alignment between the realities or requirements of a work role and an individuals’ values and beliefs can dampen work fulfillment. 

As the organization works on system-based challenges to fostering professional fulfillment, individuals can employ strategies to better align professional values with work roles. Stanford has created an initiative to improve academic faculty work-life fulfillment with this idea in mind.

The first component of the initiative focuses on career planning though identification of short and long-term goals for both work and home, paired with coaching and mentoring. One of the tools used in this process, a self-reflection guide and career planning tool, is available online and may be useful for faculty wishing to explore and discuss with one’s division director or mentor committee.

If you have ideas or thoughts about how the department and organization can foster more professional fulfillment, please discuss with your division director, or you can email Sarah Webber.

For more information, please see the full post on the Peds intranet (DOP login required).

---Sarah Webber, MD

Learner Tribute

 
Bikash Pattnaik, PhDHere's what a student had to say about Bikash Pattnaik, PhD (Assistant Professor, Division of Neonatology and Newborn Nursery): 

"I am very grateful I enrolled in your Biology of Vision course my freshman year and decided to join your research lab soon after. I’ve learned many things that have been and will be extremely valuable to me in my future career as I apply to medical school. Thank you for your time, mentorship, and support over the past four years!"

Hi-5 from a Colleague

 
Megan Peters, MDMegan Peters, MD, (Assistant Professor [CHS], Division of Pediatric Critical Care Medicine) was recognized with this Hi-5:

"You did a fantastic job on a busy day. Not only did you provide excellent care for an extremely ill baby, but things got done on the unit due to your back up. You rock! This is a collective Hi-5 from all of the nurses on day shift 4/7.”

Send a Hi-5 to a colleague through U-Connect

New Grants

 

Kari Bruckner, Dr. Kristin Shadman Receive Academic Professional Development Grants

Kristin Shadman, MDKari BrucknerResidency Program Manager Kari Bruckner and Division of Hospital Medicine Assistant Professor (CHS) Kristin Shadman, MD, each received UW-Madison Academic Professional Development Grants.

Bruckner will use her grant to attend the High Performance Leadership Series at the Wisconsin School of Business. Dr. Shadman will use hers to complete the Enhancing Caregiver Resilience: Burnout & Quality Improvement Full Course at Duke University.

These grants allow academic staff the opportunity to grow and develop their skills and talents, and adapt more easily to changing curricular, student, and societal needs.
 

Dr. Elizabeth Cox Receives UW2020 Grant to Build Research Pipeline for Personalized Diabetes Prevention and Treatment

Elizabeth Cox, MD, PhDElizabeth Cox, MD, PhD (Associate Professor, Division of General Pediatrics & Adolescent Medicine), received a two-year UW2020 grant for her project, “Building a Translational Research Pipeline to Personalize Diabetes Prevention and Treatment.” This WARF Discovery Initiative award---in conjunction with co-principal investigators Dawn Davis, MD, PhD, and Michelle Kimple, PhD (Medicine), co-investigator Jennifer Laffin, PhD, FACMG (Associate Professor [CHS], Division of Genetics & Metabolism), and numerous other collaborators---will establish the Diabetes Research Accelerator for Wisconsin (DRAW), a data registry and biobank of individuals with diabetes, as a next step toward delivering personalized diabetes care and facilitating interdisciplinary translational diabetes research at UW-Madison.

Support for this research was provided by the University of Wisconsin-Madison Office of the Vice Chancellor for Research and Graduate Education with funding from the Wisconsin Alumni Research Foundation.
 

Graduate Student in Otto Laboratory Awarded ICTR TL1 Grant

Sean Rinella, MPHSean Rinella, MPH, a research assistant in the laboratory of Mario Otto, MD, PhD (Assistant Professor, Division of Hematology, Oncology and Bone Marrow Transplant), received a two-year grant as part of the UW Institute for Clinical and Translational Research (ICTR) Predoctoral TL1 Program. This award provides support for his project, “Development of pre-clinical models and clinical applications for T cell receptor alpha beta depleted haploidentical stem cell transplant.” With Dr. Otto and Christian Capitini, MD, as mentors, Rinella will utilize a highly selective graft engineering process to examine the role of alpha beta T cell depletion in pediatric malignant and non-malignant diseases, including engraftment, immune reconstitution and function.
 

Bikash Pattnaik, PhD, Collaborating on UW2020 Grant

Bikash Pattnaik, PhDKrishanu Saha, PhD (Biomedical Engineering), will lead a team of investigators---including co-PIs Shaoqin Sarah Gong, PhD (Biomedical Engineering), Bikash Pattnaik, PhD (Assistant Professor, Division of Neonatology & Newborn Nursery), and David Gamm, MD, PhD (Ophthalmology and Visual Sciences), and other collaborators---to study genetic disorders of the eye in a two-year UW2020 grant, “Gene Editing Nanomedicines to Correct Pathogenic Mutations in Retinal Pigmented Epithelium.” This WARF Discovery Initiative project will use advances in biomaterials to generate nonviral, synthetic nanocarriers of CRISPR-Cas9 gene editing machinery for targeted delivery to the retinal pigmented epithelium (RPE) that surrounds the retina. Such research would generally expand the types of tissues that could be edited and hence the spectrum of disease where genomic medicine could have an impact.

Support for this research was provided by the University of Wisconsin-Madison Office of the Vice Chancellor for Research and Graduate Education with funding from the Wisconsin Alumni Research Foundation.
 

Two Baldwin Wisconsin Idea Endowment Grants Awarded to Pediatrics Investigators 

Mei Baker, MDChristine Seroogy, MDPrincipal Investigator Christine Seroogy, MD (Associate Professor, Division of Allergy, Immunology and Rheumatology), and Co-Principal Investigator Mei Baker, MD (Professor [CHS], Division of 
Genetics & Metabolism), received a three-year, $120,000 Baldwin Wisconsin Idea Endowment Grant for their project, “Development and Implementation of Rapid Genetic Test to Improve Health Outcomes in Wisconsin Plain Newborns.” This project aims to develop and implement state-of-the-art genetic testing for Wisconsin Amish and Mennonite, collectively called Plain, newborns---ultimately improving early diagnosis and treatment for disorders found at a higher frequency in these communities.

Elizabeth Cox, MD, PhDTonya Roberts, PhD, RN (Nursing), and Elizabeth Cox, MD, PhD, received a two-year, $120,000 Baldwin Wisconsin Idea Endowment Grant for their project, “Engaging Families as Care Partners in Community Nursing Homes.”

Funding for these awards is made possible through the generous gift to the UW-Madison from Ira and Ineva Reilly Baldwin through the Office of the Provost and Vice Chancellor for Academic Affairs.
 

Pediatrics Faculty Mentors, Students Chosen by the Shapiro Summer Research Program

Eleven Department of Pediatrics faculty are mentoring 10 University of Wisconsin School of Medicine and Public Health (SMPH) students as part of the Shapiro Summer Research Awards program. The program provides opportunities for first-year medical students to participate in eight- to 12-week summer research projects with UW-Madison faculty members on basic science, clinical, translational, public health, or health systems projects. Full list of pairings...

New Publications


Scholarly Publications


Bristow RG, Alexander B, Baumann M, Bratman SV, Brown JM, Camphausen K, Choyke P, Citrin D, Contessa JN, Dicker A, Kirsch DG, Krause M, Le QT, Milosevic M, Morris ZS, Sarkaria JN, Sondel PM, Tran PT, Wilson GD, Willers H, Wong RKS, Harari PM. Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology. Lancet Oncol. 2018 May;19(5):e240-e251. doi:10.1016/S1470-2045(18)30096-2. Review. PubMed PMID: 29726389.

Chen B, Feng Y, Frost DC, Zhong X, Buchberger AR, Johnson J, Xu M, Kim M, Puccetti D, Diamond C, Ikonomidou C, Li L. Quantitative glycomic analysis by mass defect-based dimethyl pyrimidinyl ornithine (DiPyrO) tags and high-resolution mass spectrometry. Anal Chem. 2018 May 20. doi: 10.1021/acs.analchem.8b00548. [Epub ahead of print] PubMed PMID: 29779369.

McBride JA, Lepak AJ, Dhaliwal G, Saint S, Safdar N. 2018. The wrong frame of mind. N Engl J Med. 378(18):1716-1721.

>> Related story: Changing Mindset Cures Patient and Yields New England Journal of Medicine Publication (published May 31, 2018, in Vital Signs, the UW Department of Medicine's e-newsletter)

Morris ZS, Guy EI, Werner LR, Carlson PM, Heinze CM, Kler JS, Busche SM, Jaquish AA, Sriramaneni RN, Carmichael L, Loibner H, Gillies SD, Korman AJ, Erbe AK, Hank JA, Rakhmilevich AL, Harari PM, Sondel PM. Tumor-specific inhibition of in situ vaccination by distant untreated tumor sites. Cancer Immunol Res. 2018 May 10. pii: canimm.0353.2017. doi: 10.1158/2326-6066.CIR-17-0353. [Epub ahead of print] PubMed PMID: 29748391.

Pauli RM, Legare JM. Achondroplasia. 1998 Oct 12 [Updated 2018 May 10]. In: Adam MP, Ardinger HH, Pagon RA, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1152/

Wei JS, Kuznetsov IB, Zhang S, Song YK, Asgharzadeh S, Sindiri S, Wen X, Patidar R, Nagaraj S, Walton A, Guidry Auvil JM, Gerhard DS, Yuksel A, Catchpoole DR, Hewitt SM, Sondel PM, Seeger RC, Maris JM, Khan J. Clinically relevant cytotoxic immune cell signatures and clonal expansion of T cell receptors in high-risk MYCN-not-amplified human neuroblastoma. Clin Cancer Res. 2018 May 21. pii: clincanres.0599.2018. doi: 10.1158/1078-0432.CCR-18-0599. [Epub ahead of print] PubMed PMID: 29784674.
 

Public Educational Resources


Jain AL. How often and how much should your baby eat? American Academy of Pediatrics healthychildren.org website. https://www.healthychildren.org/English/ages-stages/baby/feeding-nutrition/Pages/How-Often-and-How-Much-Should-Your-Baby-Eat.aspx. Updated March 22, 2018. Accessed June 4, 2018.

Stockhausen AL. How much formula does my baby need? American Academy of Pediatrics healthychildren.org website. https://www.healthychildren.org/English/tips-tools/ask-the-pediatrician/Pages/How-much-formula-does-my-baby-need.aspx. Updated March 22, 2018. Accessed June 4, 2018.

Stockhausen AL. How do I mix and serve infant formula for my baby? American Academy of Pediatrics healthychildren.org website. https://www.healthychildren.org/English/tips-tools/ask-the-pediatrician/Pages/How-do-I-mix-and-serve-infant-formula-for-my-baby.aspx. Updated March 23, 2018. Accessed June 4, 2018.

New Faculty and Staff


Faculty  


Katherine Lemon, MDKatherine Lemon, MD
Visiting Associate Professor
Neonatology and Newborn Nursery

Dr. Lemon was born in Madison and completed her internship and residency here at the Department of Pediatrics.


Queenie Tan, MDQueenie Tan, MD
Clinical Instructor
Genetics and Metabolism

Dr. Tan previously completed a clinical fellowship in biochemical genetics here at the University of Wisconsin School of Medicine and Public Health.  

 

Staff  

Jamee SchoephoersterJamee Schoephoerster
University Services Associate 1
Neonatology and Newborn Nursery

Jamee is a University Services Associate 1 for Dr. Mezu-Ndubuisi’s lab and the Division of Neonatology and Newborn Nursery.

We want to hear from you!


The purpose of Milestones is to celebrate achievements and foster teamwork and community within the department. 

Please contact us at news@pediatrics.wisc.edu to share information about your professional achievements in education, research, clinical care, outreach and advocacy; honors and awards; new grants or publications; or other accomplishments of interest to your colleagues. 
Copyright © 2018 University of Wisconsin Department of Pediatrics, All rights reserved.


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