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January 2023


Dear Reader,


2023 can be a return to CTSAs addressing healthcare’s ‘wicked problems’

Rob Califf’s keynote address at the Annual CTSA Program meeting last November was quite sobering and could be succinctly summarized as ‘US health is regressing.’ A recent long read in The Atlantic offers an equally sobering view on the general state of progress in the US across the technological spectrum. While the piece takes a broad brush to US science and technology, there are several relevant and interesting biomedical examples presented including smallpox and Operation Warp Speed. The overall theme of the article is that our progress has stalled even though our ‘inventions’ (what we in the biomedical fields would call ‘basic research’) continue to lead the world. The article identifies this ‘stall in progress’ as the translation of those inventions through to implementation (“The way individuals and institutions take an idea from one to 1 billion is the story of how the world really changes.”).
With a new year upon us, rather than recite the standard litanies of resolutions, it makes sense to contemplate some big picture ideas or concepts that the CTSA consortium can tackle (or at least take a bite of). While some have referred to this category as ‘big hairy problems’, I prefer the term ‘wicked problem’.


By: Michael Kurilla, M.D., Ph.D., NCATS Director of the Division of Clinical Innovation

Spotlight Story


2022 Appalachian Translational Research Network Summit Convened Health Stakeholders at University of Kentucky

Two female college students stand in front of a research poster about improving access to healthcare in rural West Virginia. Image credit: Richard Sanchez, University of Kentucky Center for Clinical &Translational Science
The 12th Annual Appalachian Translational Research Network (ATRN) Summit was hosted Nov. 14 and 15 by the University of Kentucky Center for Clinical and Translational Science. More than 200 researchers, community members and students gathered to foster collaborations, present findings and share best practices. The two-day event featured fifteen break-out sessions that included 32 oral presentations selected from abstract submissions; a poster session with 44 presentations, 20 of which were from graduate student and post-doctoral presenters who received feedback from mentors; networking and committee meetings; and an update on the impact of recent flooding in Eastern Kentucky.
The ATRN, now a 501c3 organization, comprises nine academic and medical institutions and multiple community-based organizations that are committed to addressing the significant health challenges of the region. The Network aims to serve as a conduit for enhancing research across the translational spectrum, ranging from basic science to translation to patients, practice and communities.





National COVID Cohort Collaborative (N3C) Logo

The next set of questions for new proposals for PHASTR (Public Health Answers to Speed Tractable Results) are expected to launch at the end of January 2023. View the latest updates about the effort and learn how to get involved.



$48 Million Awarded to Oregon CTSA to Build on a Bedrock of Innovation

Basic science laboratory equipment, like beakers and test tubes, overlaid with images of the globe that are network together. Image intended to represent translational science. Image credit: OHSU Research News

The $48 million Clinical and Translational Science Award, or CTSA, to OHSU from the NIH National Center for Advancing Translational Sciences funds OCTRI as part of a collaborative consortium to develop research tools, design research protocols, and provide funding and training to speed the progress of research into the community to improve human health.



Submitted by: Oregon Health & Science University


Maija Williams MPH wearing dark suit jacket and a bright salmon-colored blouse

Maija Williams, M.P.H., Promoted to Chief Operating Officer of Rockefeller University Hospital

The Rockefeller University Hospital is proud to announce the promotion of Maija Williams, M.P.H., to the position of Chief Operating Officer of the Hospital. Since joining Rockefeller University in 2006, Maija has managed the Center for Clinical and Translational Science (CCTS) and the administrative responsibilities of the Rockefeller University Hospital. She has played a vital role in the successful renewals of the Rockefeller University NIH NCATS Clinical and Translational Science Award grant since 2006, which has brought more than $135 million in grant funds to Rockefeller.


Submitted by: Rockefeller University



CLIC-CCOS Transition Corner

CTSA Coordination, Communication, & Operations Support (CCOS) logo

The new CTSA Coordination, Communication, and Operations Support (CCOS) Center has begun working with CLIC to transition CTSA Program support responsibilities. Updates can be found on the dedicated CCOS page of the CLIC website.

Recent updates include:

  • An introduction to the CCOS team and the ongoing transition
  • Details on the transition of CTSA group meeting coordination and logistics from CLIC to CCOS




Call for CTSA Images: Send NCATS Images of the CTSA Program in Action!

Veronica Smith Ruiqi Cen PhD Postdoc CPH talking with masked person at information booth.

Thank you to all who continue to submit CTSA photos for use in NCATS communications, and to refresh the CTSA Flickr account. NCATS would like to encourage your continued submission into 2023.

How to Submit Photos:

  1. Review and complete the NCATS Image and Multimedia Use Checklist to ensure you have all of the information that would be needed for the submission.
  2. Reach out by email to and with the descriptive information requested in the checklist and high resolution photos as attachments.
  3. NCATS will upload your photos to our Flickr site. If you have any questions, please reach out to



Do You Have News or a Success Story You Would Like to See in the Ansible?

Submit a feature story that you would like to be considered for an upcoming CTSA Ansible.





January CTSA Program Webinar
2-3 PM ET


NCATS January Council
1 PM-6 PM ET


Publication of the Revised NIH Grants Policy Statement (Rev. December 2022) for Fiscal Year 2023
Updates to the Non-Discrimination Legal Requirements for NIH Recipients
Leading Equity and Diversity in the Medical Scientist Training Program (LEAD MSTP) (T32). First application due date is January 25, 2023.
Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional). Deadline: February 17, 2023.
Team Science Leadership Scholars Program (LSP) in Women’s Health, Autoimmune and Immune-Mediated Diseases. Deadline February 20, 2023.
Enhancing the Use of All of Us Research Programs Data (R21 Clinical Trial Not Allowed)
Small Grants to Enhance the Use of All of Us Research Programs Data (R03 Clinical Trial Not Allowed)
National Center for Data to Health Logo


The Impact of Malnutrition in Patients Diagnosed with COVID-19


Jana Ponce and Jerrod Anzalone

Malnutrition significantly increased the risk of mortality and adverse hospital events in patients hospitalized with COVID-19. In the United States, current estimates suggest that 20-50% of hospitalized patients have malnutrition. Malnutrition is a condition that develops when the body lacks sufficient vitamins, minerals and other nutrients needed to maintain healthy tissues and organ function. In hospitalized patients, malnutrition has been associated with poor outcomes, including increased risk of infection, increased length of stay, and higher in-hospital mortality rates.


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