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CLIC Center for Leading Innovation & Collaboration
News Roundup
April 20, 2021
CTSA News            CLIC Updates            CLIC Education            ICYMI            Coordinating Center News
News from around the CTSA Program Consortium
Gordana Vunjak-Novakovic

Columbia IICTR Narratives of Discovery: Gordana Vunjak-Novakovic

Gordana Vunjak-Novakovic is a tissue engineer at Columbia University, internationally renowned for her synthesis of human tissue from biologic antecedents cultivated on biomatrices. She “grows” cartilage for joint repair, bone for facial bone reconstruction and human myocytes for reconstitution of infarcted heart tissue. 

Medical illustration of senescent cells, greenish, among normal cells.

Balancing Damage and Protection, Neutrophils May Lead to Cell Aging, Mayo study says

The action of an immune cell called a neutrophil may contribute to tissue aging, according to a new study. As neutrophils do their job, they may damage chromosomes in nearby cells which, over time, may lead to cellular senescence. This new concept may help clarify cell aging. It also suggests targeting neutrophils might be helpful in the treatment of age-related disease.

This research was funded, in part, by the Mayo Clinic Center for Clinical and Translational Science.

 A child is screened for congenital heart disease in China using the alpha version of a software application supported with ODAT grant funding.
Photo courtesy of One Heart Health. A child is screened for congenital heart disease in China using the alpha version of a software application supported with ODAT grant funding.

ODAT supports innovations to improve health equity and accessibility

New healthcare innovations have the potential to improve health equity and accessibility. The University of Minnesota CTSI’s Office of Discovery and Translation (ODAT) is supporting the development of novel solutions designed to reduce health disparities due to geographic location, race, gender, socioeconomic status, disability, sexual identity and orientation.

Data Science to Power Implementation with Social Determinants of Health

Have you wondered how to make data work for you, how to make sense of the deluge of data, and how to use data to help in your day-to-day clinical, policy and other decisions? If this sounds like you, mark your calendar to attend "Data Science to Power Implementation with Social Determinants of Health," the inaugural conference presented by the Data to Action! program. This online conference is supported by NCATS.

Friday, April 30, 8:15 a.m. - 4 p.m. Register here 

Large Clinical Trial to Study Repurposed Drugs to Treat COVID-19 Symptoms

The National Institutes of Health will fund a large, randomized, placebo-controlled Phase 3 clinical trial to test several existing prescription and over-the-counter medications for people to self-administer to treat symptoms of COVID-19. Part of the Accelerating COVID 19 Therapeutic Interventions and Vaccines (ACTIV) public–private partnership, the ACTIV-6 trial aims to provide evidence-based treatment options for the majority of adult patients with COVID-19 who have mild-to-moderate symptoms and are not sick enough to be hospitalized. NIH will provide an initial investment of $155 million in funding for the trial.

Updates from CLIC  

COVID Stories of Impact now LIVE on the CLIC website


It's been over a year since the start of the pandemic, and CTSA Program hubs have been on the forefront of COVID-19 research. Read how hubs pivoted to developing COVID testing, treatments and methods of prevention early in the pandemic.

Introduction to CM-PRISM Webinars

Common Metrics – Program Results to Improve Strategic Management, aka CM-PRISM, is the new data reporting software platform for CTSA Program hubs to report their annual Common Metrics data and narratives. This new platform was built in REDCap, which is familiar software to many hubs across the consortium. This new platform has the flexibility to accommodate multiple users from each hub and to ease the burden of data entry.

The goal of this new platform is to increase the consistency and comparability of hub data across the consortium. CM-PRISM has been designed to support the updates made by the Informatics and Careers Metric Quality Improvement committees.

Two “How to Use CM-PRISM” webinars have been scheduled. Hubs are encouraged to register for the webinar that best fits their schedules. The webinars will be recorded and can be accessed on the Common Metrics Webinar page.

Thursday, May 6 at 2 pm ET ~ OR ~or Monday, May 17 at 3 pm ET.

CLIC Education

The CLIC Career Development Community has launched!

This is an interactive space available to the CTSA Program and greater translational science communities where individuals can collaborate, network, and share ideas with their peers. There are three focus areas for KL2 scholars, TL1 trainees and clinical research professionals. Each focus area includes a message board, community content feed and searchable community member list to foster communication across the consortium.

Join now!

NCATS Life Course Research Visual Toolkit

After an exciting launch party during the CTSA Spring Program Meetings on April 14, the NCATS Life Course Research Visual Toolkit is officially live! The toolkit, titled Charting the Life Course: An Interdisciplinary Blueprint, is available in the CLIC Education Clearinghouse and Life Course Visual Toolkit YouTube Channel. It includes six recorded webinars, plus shorter five to 15-minute videos for anyone interested in learning more about life course research methods and applications. Congratulations to the team for their work on this valuable resource!

Read more here!

ICYMI: News from the Science & Research World

Clintoria Williams, co-founder of #BlackInPhysiology and a principal investigator at Wright State University, researching kidney pathophysiology. Credit: Nature.com

Black scientists gather to form communities and boost diversity in science

Last fall, sparked by the Black Lives Matter movement and triggered by the #BlackBirdersWeek virtual event, several scientific communities took to social media to create ‘#BlackIn...’ movements. Over the course of a week, organizers offered virtual talks, workshops and social events highlighting Black scientists in their fields. We spoke with the founders of four of these ‘#BlackIn...’ movements to learn how they are empowering the Black scientific community to start conversations about being Black in science, and to discuss strategies for continuing to diversify scientific research.

CTSA Program Coordinating Centers' News

Trial Innovation Network logo

Team Science: Empowering Effective Multi-Center Research Collaborations

 

By the end of this presentation, viewers will be able to:

  1. Define team science and differentiate team science research from more traditional forms
  2. Identify how team science is promoted by the NIH
  3. Explain the benefits and shortcomings of team science research
  4. Describe the risks associated with team science models and how to overcome them
  5. Describe real-world examples of how team science research has been integrated in the past within the TIN
  6. List and define the key steps in developing a team science framework for a research proposal


May 3, 2021 at 12pm ET. 

National Center for Data to Health logo

Examining a Connection Between HIV, COVID-19 and Race

It has been well-documented that racial disparities exist in the incidence rates of people diagnosed with HIV. And separately, with the emergence of the COVID-19 pandemic, the prevalence of the Non-Hispanic (NH) Black and Hispanic people being disproportionately diagnosed with the virus, and suffering higher mortality rates, has also been a disturbing trend.

A new study looked at the potential conflation of HIV and COVID-19, and if there were racial disparities to be discovered within the combination of these two health issues.

If you have a story, opportunity, project or event that you'd like included in the News Roundup, please contact CLIC Communications: clic_comms@clic-ctsa.org or visit the CLIC Library to learn how to post  content to the CLIC website

The University of Rochester Center for Leading Innovation and Collaboration (CLIC) is the coordinating center for the Clinical and Translational Science Awards (CTSA) Program, funded by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH), Grant U24TR002260.
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